2012年度業績

1.原著論文

• Diagnostic and prognostic impact of serum-soluble UL16-binding protein 2 in lung cancer patients.
  Yamaguchi K, Chikumi H, Shimizu A, Takata M, Kinoshita N, Hashimoto K, Nakamoto M, Matsunaga S, Kurai J, Miyake N, Matsumoto S, Watanabe M, Yamasaki A, Igishi T, Burioka N, Shimizu E
  .Cancer Sci 103(8):1405-13　2012
• Threonine 2609 phosphorylation of the DNA-dependent protein kinase is a critical prerequisite for epidermal growth factor receptor-mediated radiation resistance.
  Javvadi P, Makino H, Das AK, Lin YF, Chen DJ, Chen BP, Nirodi CS.
  Mol Cancer Res. 10(10):1359-68　2012
• Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma.
  Kurai J, Chikumi H, Hashimoto K, Takata M, Sako T, Yamaguchi K, Kinoshita N, Watanabe M, Touge H, Makino H, Igishi T, Hamada H, Yano S, Shimizu E.
  Int J Oncol.;41(5):1610-8、2012
• Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer.
  Takeuchi S, Wang W, Li Q, Yamada T, Kita K, Donev IS, Nakamura T, Matsumoto K,Shimizu E, Nishioka Y, Sone S, Nakagawa T, Uenaka T, Yano S.
  Am J Pathol. 181(3):1034-43、2012
• Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells.
  Miyake N, Chikumi H, Takata M, Nakamoto M, Igishi T, Shimizu E.
  Oncol Rep. 28(3):848-54. 2012
• Infective endocarditis caused by Achromobacter xylosoxidans: a case report and review of the literature.
  Tokuyasu H, Fukushima T, Nakazaki H, Shimizu E.
  Intern Med　51(9):1133-8. 2012
• Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
  Takata M, Chikumi H, Miyake N, Adachi K, Kanamori Y, Yamasaki A, Igishi T, Burioka N, Nanba E, Shimizu E.
  Cancer Biol Ther. 13(6):369-78. 2012
• Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues.
  Hirota T, Date Y, Nishibatake Y, Takane H, Fukuoka Y, Taniguchi Y, Burioka N,Shimizu E, Nakamura H, Otsubo K, Ieiri I.
  Lung Cancer. 77(1):16-23. 2012
• A case of pulmonary sarcoidosis complicated with bronchial asthma that proved eosinophilic invasion].
  Harada T, Kawasaki Y, Touge H, Tokuyasu H, Yamasaki A, Shimizu E.
  Arerugi. 61(12):1744-8. 2012