研究紹介

2005年度業績

  • Prostaglandin E2 promotes colon cancer cell growth through a novel Gs-Axin-beta-catenin signaling axis.
    Castellone MD, Teramoto H, Williams BO, Druey KM and Gutkind JS.
    Science 310 (5753):1504?10, 2005
  • Glucocorticoid administration increases hPer1 mRNA levels in human peripheral blood mononuclear cells in vitro or in vivo.
    Fukuoka Y, Burioka N, Takata M, Ohdo S, Miyata M, Endo M, Shimizu E.
    J Biol Rhythms 20(6):550-553, 2005
  • Dexamethasone influences human clock gene expression in bronchial epithelium and peripheral blood mononuclear cells in vitro.
    Burioka N, Takata M, Okano Y, Ohdo S, Fukuoka Y, Miyata M, Takane H, Endo M, Suyama H, Shimizu E.
    Chronobiol Int 22(3):585-90, 2005
  • Dexamethasone inhibits phosphorylation of histone H3 at serine 10.
    Hasegawa Y, Tomita K, Watanabe M, Yamasaki A, Sano H, Hitsuda Y, Shimizu E.
    Biochem Biophys Res Commun 336(4):1049-55,2005
  • Beta2-adrenoceptor agonists induce the mammalian clock gene, hPer1,mRNA in cultured human bronchial epithelium cells in vitro.
    Takata M, Burioka N, Ohdo S, Fukuoka Y, Miyata M, Endo M, Suyama H, Shimizu E.
    Chronobiol Int 22(4):777-83,2005
  • Defects in apoptotic signal transduction in cisplatin-resistant non-small cell lung cancer cells.
    Ikuta K, Takemura K, Kihara M, Naito S, Lee E, Shimizu E, Yamauchi A.
    Oncol Rep 13(6):1229-1234,2005
  • Expression of multidrug resistance proteins and accumulation of cisplatin in human non-small cell lung cancer cells.
    Ikuta K, Takemura K, Sasaki K, Kihara M, Nishimura M, Ueda N, Naito S, Lee E, Shimizu E, Yamauchi A.
    Biol Pharm Bull 28(4):707-712,2005
  • Overexpression of constitutive signal transducer and activator of transcription 3 mRNA in cisplatin-resistant human non-small cell lung cancer cells.
    Ikuta K, Takemura K, Kihara M, Nishimura M, Ueda N, Naito S, Lee E, Shimizu E, Yamauchi A.
    Oncol Rep 13(2):217-222,2005
  • Measurement of Pseudomonas aeruginosa multidrug efflux pumps by quantitative real-time polymerase chain reaction.
    Yoneda K, Chikumi H, Murata T, Gotoh N, Yamamoto H, Fujiwara H, Nishino T, Shimizu E.
    FEMS Microbiol Lett 243(1): 125-31,2005
  • Suppression of phosphatidylinositol 3-kinase/Akt signaling pathway is a determinant of the sensitivity to a novel histone deacetylase inhibitor, FK228,in lung adenocarcinoma cells.
    Kodani M, Igishi T, Matsumoto S, Chikumi H, Shigeoka Y, Nakanishi H, Morita M, Yasuda K, Hitsuda Y, Shimizu E.
    Oncol Rep 13(3): 477-83,2005
  • The Tottori-Ken Seibu earthquake and exacerbation of asthma in adults.
    Tomita K, Hasegawa Y, Watanabe M, Sano H, Hitsuda Y, Shimizu E.
    J Med Invest 52(1,2): 80-84,2005
  • Approximate entropy in electroencephalogram during wake and sleep.
    Burioka N, Miyata M, Corn´elissen G, Halberg F, Takeshima T, Kaplan DT, Suyama H, Endo M, Maegaki Y, Nomura T, Tomita Y, Nakashima K, Shimizu E.
    Clin EEG Neurosci. 36(1): 21-4,2005
  • Alteration of circadian rhythms in peak expiratory flow of nocturnal asthma following nighttime transdermal β2-adrenoceptor agonist tulobuterol chronotherapy.
    Burioka N, Miyata M, Endo M, Fukuoka Y, Suyama H, Nakazaki H, Igawa K, Shimizu E.
    Chronobiol Int 22(2): 383-390,2005
  • Distribution of phenotypically disparate myocyte subpopulations in airway smooth muscle.
    Halayko AJ, Stelmack GL, Yamasaki A, McNeill K, Unruh H, Rector E.
    Can J Physiol Pharmacol 83(1):104-16,2005
  • Autocrine activation of an Osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.
    Teramoto H, Castellone MD, Malek RL, Letwin N, Gutkind JS and Lee NH.
    Oncogene 24(3): 489-501,2005
  • Approximate entropy of the electroencephalogram in healthy awake subjects and absence epilepsy patients.
    Burioka N, Cornelissen G, Maegaki Y, Halberg F, Kaplan DT, Miyata M, Fukuoka Y, Endo M, Suyama H, Tomita Y, Shimizu E.
    Clin EEG Neurosci 36(3):188-93,2005
  • Pharmacokinetic and pharmacodynamic comparison of fluoropyrimidine derivatives, capecitabine and 5'-deoxy-5-fluorouridine(5'-DFUR).
    Ebi H, Sigeoka Y, Saeki T, Kawada K, Igarashi T, Usubuchi N, Ueda R, Sasaki Y, Minami H.
    Cancer Chemother Pharmacol 56(2):205-11, 2005
  • Underrecognition of the severity of asthma and undertreatment of asthma in a rural area of Japan.
    Tomita K, Hanaki K, Hasegawa Y, Watanabe M, Sano H, Igishi T, Burioka N, Hitsuda Y, Horimukai K, Fukutani K, Sugimoto Y, Yamamoto M, Kato K, Ikeda T, Konishi T, Tokuyasu H, Kawasaki Y, Yajima H, Sejima H, Isobe T, Takabatake T, Shimizu E; San-in Asthma Research Group.
    J Asthma 42(8):689-96, 2005
  • 定量的PCR法を用いた緑膿菌の薬剤排出ポンプ発現量の測定
    米田一彦,山本司生,千酌浩樹
    米子医学雑誌 56:5-20,2005
  • ヒト末梢血単核球を用いた時計遺伝子発現に対するグルココルチコイドの影響
    服岡泰司,鰤岡直人
    米子医学雑誌 56:72-84,2005
  • 慢性閉塞性肺疾患(COPD)早期診断のための中高年喫煙者対象スパイロメトリー検診
    片山 覚
    米子医学雑誌 第57巻2号 89-98, 2005
  • Des-γ-carboxy prothrombin(PIVKA-II)-producing mediastinal embryonal carcinoma with features of hepatoid differentiation.
    Hasegawa Y, Tomita K, Hashimoto K, Shigeoka Y, Watanabe M, Yamasaki A, Shimizu E.
    Anticancer Res 25(6C):4569-71,2005
  • Anaphylactic shock caused by exposure to sea anemones.
    Nagata K, Hide M, Tanaka T, Ishii K, Izawa M, Sairenji T, Tomita K, Shimizu E.
    Allergol Int 2005
  • がん治療における分子標的薬 Q&A ゲフィチニブ(イレッサ)
    重岡 靖,清水英治
    薬局 56(4): 84-9,2005,南山堂.
  • 特集 肺癌の制圧を目指して 高齢者の肺癌治療
    陶山久司,清水英治
    成人病と生活習慣病 35(3): 311-17,2005.
  • 最近の肺炎:病原別化学療法の実際 真菌性肺炎
    井川克利, 清水英治
    臨牀と研究82(12):1948?52.2005
  • ギンスバーグ肺癌
    江口研二,清水英治監訳,
    翻訳:石井博司,関 順彦,谷垣俊守,瀬戸貴司,中野真規子,中村廣繁,陶山久司,鰤岡直人
    アメリカ癌学会 臨床腫瘍学カラーアトラス,西村書店,東京,2005.
  • 肺膿瘍,嚥下性肺炎
    櫃田 豊,井岸 正,安田和人
    実践 抗生物質・抗菌薬療法ガイド―縮刷版―.文光堂,東京,p262-4,2005.
  • 細胞医療固形腫瘍に対するミニ移植 その他の固形腫瘍
    陶山久司,金成 元 高上洋一編,医薬ジャーナル社,大阪,200-8,2005
  • 肺癌の早期診断に関する調査
    清水英治,千酌浩樹,重岡 靖,陶山久司,井岸 正
    鳥取県健康対策協議会疾病構造の地域特性調査対策専門委員会報告
    第20集(平成16年度)pp14-16,2005
  • わかりやすいキーワード解説 呼吸器インターベンション
    陶山久司,清水英治
    コンセンサス癌治療 4(1): 53,2005
  • 非小細胞肺癌におけるレキシノイドの新たな役割:ベキサロテン
    陶山久司 Lung cancer up date 5,1,2005.

文献抄録

  • 肺腺癌に対するUFTによる術後補助化学療法の無作為比較試験
    重岡 靖,清水英治
    コンセンサス癌治療 4(1): 54,2005.
  • 転移性非小細胞肺癌に対する化学療法の役割について:臨床医の知識と傾向の調査
    重岡 靖
    Lung Cancer Update 2: 5,2005,THOMSON.

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